Europace Advance Access originally published online on April 4, 2008
Europace 2008 10(5):618-623; doi:10.1093/europace/eun071
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SPORTS AND ATRIAL FIBRILLATION
Long-term endurance sport practice increases the incidence of lone atrial fibrillation in men: a follow-up study
1 Cardiology Department, Hospital del Mar, Passeig Marítim 25-29, 08003 Barcelona, Spain; 2 CIBER en Epidemiología y Salud Pública (CIBERESP), Spain; 3 Institut del Torax, Hospital Clínic Universitari de Barcelona, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain; 4 Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d'Investigació Mèdica (IMIM), Barcelona, Spain
Aims: The aim of this study is to determine the incidence of lone atrial fibrillation (LAF) in males according to sport practice and to identify possible clinical markers related to LAF among marathon runners.
Methods and results: A retrospective cohort study was designed. A group of marathon runners (n = 252) and a population-based sample of sedentary men (n = 305) recruited in 1990–92 and 1994–96, respectively, were contacted in 2002–03 and invited to attend an outpatient clinic to identify suggestive symptoms of having experienced an arrhythmia requiring medical attention. In those with suggestive symptoms of atrial fibrillation, medical records were reviewed. Finally, LAF was diagnosed on the basis of the presence of atrial fibrillation in an electrocardiographic recording. In the group of marathon runners, an echocardiogram was performed at inclusion and at the end of the study. The annual incidence rate of LAF among marathon runners and sedentary men was 0.43/100 and 0.11/100, respectively. Endurance sport practice was associated with a higher risk of incident LAF in the multivariate age- and blood pressure-adjusted Cox regression models (hazard ratio = 8.80; 95% confidence interval: 1.26–61.29). In the group of marathon runners, left atrial inferosuperior diameter and left atrial volume were both associated with a higher risk of incident LAF.
Conclusion: Long-term endurance sport practice is associated with a higher risk of symptomatic LAF in men. This risk is associated with a larger left atrial inferosuperior diameter and volume in physically active subjects.
Key Words: Atrial fibrillation, Exercise, Incidence
* Corresponding author. Tel: +34 93 248 30 00; fax: +34 93 225 75 50.E-mail address: lmolina{at}imas.imim.es
Manuscript submitted 6 September 2007. Accepted after revision 4 March 2008.