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Europace Advance Access originally published online on August 18, 2008
Europace 2008 10(10):1189-1194; doi:10.1093/europace/eun212
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Pacing

Influence of DDD rate response pacing with integrated double sensors on physical efficiency and quality of life

Eugeniusz Pilat, Rafal Mlynarski*, Agnieszka Wlodyka and Wlodzimierz Kargul

Department of Electrocardiology, Upper-Silesian Cardiology Center, The Medical University of Silesia, ul. Ziolowa 45/47, Katowice 40-635, Poland

Aims: The aim of this study was to evaluate whether the use of a double sensor gives additional benefits for patients in improving physical efficiency as well as quality of life (QoL) as compared to the accelerometer sensor alone.

Methods and results: The presented research is a prospective, randomized, single-blind clinical trial. Double-sensor (accelerometer and minute-ventilation) pacemakers (Guidant, Pulsar Max DR) were implanted in 20 patients with sinus node dysfunction (SND) and chronotropic incompetence. After randomization, patients were placed in one of two groups: 1, only the accelerometer sensor was activated; 2, both sensors were activated. After a 3-month follow-up, an initial cardio-pulmonary exercise test was performed, after which the patients were placed in the opposite group for a further 3 months. Finally, the second tests were performed. In 75% of the patients an improvement in QoL was observed in the double-sensor group (P = 0.0242) when compared with the single-sensor group. The addition of a ventilating sensor had no influence on the duration of exercise test (A: 11 ± 3.19 vs. B: 11 ± 2.92 P = 1.0000). The parameters of cardio-pulmonary exercise tests recorded in situations A and B before exertion, and 6 minutes after exertion were not statistically different.

Conclusion: The use of double-sensor pacemakers does not improve physical efficiency; however, it does improve QoL.

Key Words: Rate response pacemaker, Quality of life, Cardio-pulmonary exercise test

* Corresponding author. Tel: +48 32 3598893; fax: +48 32 2524098. E-mail address: rafal_mlynarski{at}mp.pl

Manuscript submitted 19 April 2008. Accepted after revision 25 July 2008.


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