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Europace Advance Access published online on June 3, 2008
Europace, doi:10.1093/europace/eun149
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

CASE REPORT

Successful cardiac resynchronization therapy after heart transplantation

Astrid Apor1, Valentina Kutyifa1, Béla Merkely1,*, Szabolcs Szilágyi1, Péter Andrássy2, Tivadar Hüttl3, Márta Hubay4, Attila Róka1 and László Gellér1

1 Heart Centre, Semmelweis University, Budapest, Hungary; 2 Cardiology Department, Bajcsy-Zsilinszky Hospital, Budapest, Hungary; 3 Department of Cardiovascular Surgery, Semmelweis University, Budapest, Hungary; 4 Department of Forensic Medicine, Semmelweis University, Budapest, Hungary

We describe a case of a 56-year-old male patient, who developed refractory dilated cardiomyopathy 5 years after heart transplantation. An atriobiventricular pacemaker was implanted when indication criteria of cardiac resynchronization therapy (CRT) were seen. The intraventricular dyssynchrony was significant before CRT, while synchronous contraction was demonstrated later with the beneficial reverse remodelling of the left ventricle. Resynchronization therapy resulted in significant improvement of the patient's clinical parameters. The success of this therapy points out the possible role of CRT in the treatment of chronic allograft failure after heart transplantation.

Key Words: cardiac resynchronization therapy, heart transplantation, heart failure

* Corresponding author. Tel: +36 20 825 80 35; fax: +36 20 458 68 42. E-mail address: merkely.bela{at}kardio.sote.hu

Manuscript submitted 1 April 2008. Accepted after revision 12 May 2008.


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